cchiomova

Hericium erinaceus

Lion's Mane

CognitionNGF synthesisNeuroplasticityAnxiety
CategoryCognitive
Dose500–3,000 mg/day
Beta-glucan25–40%
TimingMorning + midday with food
Hericium erinaceus

Key compound

Hericenones & Erinacines

Overview

Lion's mane is the only functional mushroom known to stimulate nerve growth factor (NGF) synthesis. The hericenones (fruiting body) and erinacines (mycelium) cross the blood-brain barrier and promote neurogenesis. A 2009 double-blind trial found significant cognitive improvement at 1,000 mg three times daily in adults with mild cognitive impairment.

Primary citation

Mori K, Inatomi S, Ouchi K, et al. · 2009

Improving effects of Yamabushitake on mild cognitive impairment: a double-blind placebo-controlled clinical trial

Phytother Resdoi:10.1002/ptr.2634PubMed 18844328 ↗

Calculate your dose

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Lion's mane calculator →
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For informational purposes only. Not intended to diagnose, treat, cure, or prevent any disease. Consult a qualified healthcare provider before beginning any supplement protocol.