Lentinula edodes
Shiitake
ImmunityAHCCCardiovascularSkin
Category
Immune
Dose range
500–2000 mg
Beta-glucan
25–40%
Timing
Any time with food
Key compound
Lentinan & AHCC
Overview
Shiitake contains lentinan, a beta-1,3 glucan approved as an oncology adjuvant in Japan, and is the source of AHCC (Active Hexose Correlated Compound), the most widely studied specialty mushroom compound in oncology. AHCC has over 30 human clinical trials and demonstrated effects on NK cell activity.
Primary reference
Dai X, Stanilka JM, Rowe CA, et al. · 2015
Consuming Lentinula edodes (Shiitake) mushrooms daily improves human immunity
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Adjusted for bodyweight and extract form